Review: moderately early postnatal corticosteroids reduce chronic lung disease and mortality in preterm infants, but increase complications.

Review: early postnatal corticosteroids reduce chronic lung disease in preterm infants, but increase complications.

Postnatal corticosteroids in preterm infants: systematic review of effects on mortality and motor function.

BACKGROUND Postnatal corticosteroid therapy has been proved in randomized controlled trials to reduce ventilator dependence and the rate of chronic lung disease in preterm infants with few serious short-term side effects. However, there are other consequences that might follow postnatal corticosteroid therapy that are more important, including mortality or cerebral palsy. OBJECTIVES To review...

Postnatal corticosteroids to treat or prevent chronic lung disease in preterm infants.

This statement is intended for health care professionals caring for neonates and young infants. The objectives of this statement are to review the short and long term effects of systemic and inhaled postnatal corticosteroids for the prevention or treatment of evolving or established chronic lung disease, and to make recommendations for the use of corticosteroids in infants with very low birth w...

Bronchopulmonary dysplasia.

Introduction Many advances in neonatology in the last several decades have allowed for the resuscitation, support, and survival of more preterm infants. The mortality associated with respiratory disease in this population of micropremies has been altered significantly by the use of antenatal corticosteroids, postnatal surfactant, improved respiratory support technology, and enhanced nutritional...

A three year follow up of preterm infants after moderately early treatment with dexamethasone.

OBJECTIVE To assess the effect of moderately early postnatal dexamethasone treatment on growth and neurodevelopmental outcome in preterm infants. METHODS Thirty preterm infants enrolled in a randomised clinical trial to investigate the effectiveness of moderately early dexamethasone administration in the treatment of chronic lung disease were routinely followed up. Fifteen babies received a t...